MAINTENANCE: 15 mg/kg (max 3000 mg) IV Q 4 hours LOAD: 100 mg/kg IV (max 6000 mg given over 30 minutes) Severe intoxication with lipophilic drug (cyclic antidepressants, bupropion, calcium channel blockers, beta blockers) INFUSION: 1-10 unit/kg/hour continuous IV infusion MAINTENANCE: 10 mg/kg IV Q 12 hours for 4 doses then 15 mg/kg IV Q 12 hours thereafterĥ g IV given as two consecutive 2.5 g IV boluses
Lead, mercury, arsenic, gold, antimony, bismuth, lead, nickel, polonium x weight (kg)/100 kg = # of vialsĮach vial is expected to bind 500 mcg of ingested digoxinĭimercaptosuccinic acid (DMSA) (succimer, Chemet)ġ0 mg/kg PO TID for 5 days then 10 mg/kg PO BID for 14 daysģ-5 mg/kg IM Q 4-6 hours (contraindication peanut allergy) Iron, aluminum, manganese, neptunium, plutoniumĭigoxin, cardiac glycosides (oleander, foxglove, red squill, bufo toad) Pediatric: 0.25 mg/kg/day in 4 divided dosesġ-2.5 mg/kg IV (repeat until symptoms subside)(max 10 mg/kg)ĭantrium (20 mg/vial): 35 vials Ryanodex (250mg/vial): 3 vials MAINTENANCE: 1-4 mg IV once or twice/daily (max 6 mg/day)Ĭadmium, chromium, cobalt, copper, iridium, lead, manganese, mercury, nickel, plutonium, ruthenium, yttrium, zinc, zirconiumĬalcium channel blockers, hydrofluoric acidĬyanide Antidote Kit (Nithiodote) (also see hydroxocobalamin)Īdult: 12 mg PO or NG initially then 8 mg Q 6 hours (32 mg max/day) Organophosphate, carbamate insecticides, muscarine containing mushroomsġ-2 mg IV or IM (can repeat up to 4 mg initially)
Pediatric: 0.05-0.1 mg/kg/dose IV Q 5-15 minutes Per manufacturer recommendation based on last dose of factor Xa inhibitorįactor Xa inhibitor direct-acting oral anticoagulantĪdult: 1-3 mg IV bolus, repeat 1-5 mg IV Q 2-20 minutes Amanita phalloides), chloroform, carbon tetrachloride, pennyroyal oilĪll oral ingestions besides hydrocarbons, alcohols, metals, corrosives, and foreign objects Quantity to Treat One 70 kg Patient for 24 Hours*īlack Widow Spider Antivenin (Lactrodectus mactans) (equine)ġ vial in 10-50 mL 0.9% sodium chloride IV over 15 minutesĬoral Snake Antivenin (Micrurus fulvius) (equine)Įastern or Texas coral snake envenomationĬrotalidae Polyvalent Immune F(ab’)2 (equine) (AnaVip®)Ĭrotalidae Polyvalent Immune Fab (ovine) (CroFab®)Īcetaminophen, cyclopeptide containing mushrooms (e.g.
The information herein is intended for educational purposes and should not be used to supersede clinical judgement or toxicologic consultation. There are multiple factors that affect a patient’s presentation and treatment options.
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